=== North towards Extremadura ([[Merida]], Badajoz, etc.) & Castilla y León ===
Go to the Estacion de Autobuses Plaza de Armas (main station) and take the line bus 41 (confirmed) towards Camas and Santiponce. The ticket costs 1'55€ (c. 2016). Ask the bus driver for la "ultimata parada" (last stop) in Santiponce, from which it's a short (15 min.) walk to El Camino de Santiago (yay!) and also an on-ramp for the Highway 803 to Mérida. (Tip: Nihilobstat got super lucky because during the oranges season a man sets a stand right there to sell oranges, and some extra cars stop there because they know about it :-) )
Warning!: The annoying thing about this route is that you're mostly going to be village hopping - cars tend to be going from small village to small village - and you'll probably wind up waiting at some pretty random on-ramps where there's not a lot of traffic. Still, it's totally doable. 2016 trip took ~6 hours from Sevilla to Mérida. If you're stuck, it's useful to remember that there is a [https://www.google.com/maps/place/Sevilla,+Espa%C3%B1a/@37.6323914,-6.1470638,16z/data=!4m5!3m4!1s0xd126c1114be6291:0x34f018621cfe5648!8m2!3d37.3890924!4d-5.9844589 big roundabout] near El Garrobo in the middle where it's easier to find a ride. ''This trip was the only time when I lost faith in hitchhiking. The road was almost empty and none of the cars passing stopped, I walked for 2-3 hours until I got to the roundabout El Garrobo. Lola, February 2019.'' Option 1
Go to the Estacion de Autobuses Plaza de Armas (main station) and take the line bus 41 (confirmed) towards Camas and Santiponce. The ticket costs 1'''LINK:''' [https://maps55€ (c.google2016).com/maps?q=Sevilla Ask the bus driver for la "ultimata parada" (last stop) in Santiponce,+Espa%C3%B1a&hl=es&ie=UTF8&ll=37.431025,-6.031164&spn=0from which it's a short (15 min.000967,0.002044&sll=40.954646,) walk to El Camino de Santiago and also an on-5.708583&sspn=0ramp for the Highway 803 to Mérida.001301,0.002044&oq=sevilla&t=h&hnear=Sevilla,+Andaluc%C3%ADa,+Espa%C3%B1a&z=19] Option 2 petrol station
2nd option. (Honestly probably not worth it)
Follow the directions above. Then follow the Camino santiago trail through the fields after 40minutes you should see petrol station on your left. Pass underneath the highway and you should be there. Takes about an hour to walk. This petrol station serves both the highway and the route nacional and plenty of cars stop here going in all directions.