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Take a bus going to [[Tipitapa]] (6 Cordobas). There is the [[Pan-American Highway|Panamericana]] which leads south to [[Granada (Nicaragua)|Granada]] and north to [[Matagalpa]] and [[Esteli]]. In between Managua and [[Tipitapa]] is the National and the International Airport of Nicaragua so if you don't have to go into Managua it's recommendable to take the bus right in front of the airport going to [[Tipitapa]] and get a ride there.