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There is a [[toll station]] just before Niš. There you can get rides straight to [[Sofia]], which is only 190 km away, and south towards [[Macedonia]] and [[Skopje]].

Hitching on the main road going east from central Niš (which runs just below the fortress and a central square) seems to work fine. This city's prime street is called Voždova (Вождова) which continues eastwards by the Skull Tower and Mediana Roman archeological site towards Niška Banja (Нишка Бања) - small neighborhood with spa centers and parks, on the mountain slopes, street changing name into boulevard of Zoran Đinđić and later boulevard of Constantine the Great. Since there are 8 km between the central square and the first hitch point, you better take city bus to Niška Banja from the central square (one way ticket should be some 45 RSD, which is about 0,4 EUR, conductors will charge it once you get on the bus). Get off the bus on the stop before the last one, that is the one right after the bus cross over the railroad lines, and should be some 15 minutes of a ride. There, it is easy spot a traffic roundabout and your hitchhiking position is right after the roundabout, towards the mountains. Here, you may catch 70% of all locals driving out of the city to your direction.

Alternative and possibly easier way to get to Prosek hitchhiking point is to get one of those suburban buses that go around local villages. Get to the main bus station just around the fortress, don't enter main terminals but find a smaller one with only one ticket selling booth (looks like a bus stop with buses constantly flowing through, just by the street, and not by fortress walls), and get on a bus to village of Prosek (Просек). Ticket should not be more than 1 EURO, and these buses depart at every 60 minutes or so. Ask driver to let you know where to get off as this is still a local suburban bus line and stops aren't well marked. Once you get off the bus, you should walk some 100 meters backwards and there you are, right at the position described above.

You have three options: bus lines Komren, Soborska,and Donja Vrežina.

Map on http://www.serbiatravelers.org/en/index.php/hitchhiking/155-nis

Take bus 10 from Vozdova Street in the direction of 9. Maj to the last stop. Bus ride is 40D. Walk to the west edge of the village. There is plenty of visibility and space for cars to pull off. I got a ride within 30 minutes.