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From the main station ask your way to Jonan-Gu-Shrine. It's basically a　little west from the main station and then about 2 miles south down one and the same road. Once you get to cross a small canal you can see the ramp on to Meishin Expy, which goes west-east, so from Osaka to Tokyo and on. Best position yourself in front of the McDonaldMcD's just before the bridge to go east to Nagoya/Tokyo. Oh, and of course, learn the Kanji writing of the place you want to go to and make a sign.