Going South to Los Angeles
If you're not in a hurry, take the Route 1. Other the US-101 is probably your best bet.
If you try to go to the I-5, be aware that the I-152 and the I-5 intersection is just highways. Don't even try to wait there for a ride. It's better to start walking down South and hope to get picked up by a friendly soul coming down from Bay Area. trash:Santa Cruz