<map lat='37.10174121753592' lng='-8.674736022949219' zoom='13' view='0' float='right'/> Lagos is a sea-side city, in the west of the Algarve region of Portugal.
From the main avenue, head east towards the main bus station. Walk past the bus station and turn right at the roundabout. Keep following this road and you should end up on the N125, which leads to the A22. If you continue on this road, there are a few good hitching spots, otherwise you can walk about 1 - 2 kilometres farther and you will reach a petrol station. Another point to start your walk to the petrol station could be the harbour, with a supermarket north of it right beside the N125.
Sputz tried hitching here in various spots for one hour and managed to obtain a ride from the petrol station all the way to Faro. This also is the best route to go north, towards Lisbon and even Porto.
Hitchhiking from Setubal (one hour by train from Lisboa) to Villa d'Obispo is easy in the summer time, just follow the coastal roads (N261, N120, N268). People stop easily, because there are no bus lines, so they often take local hitchhikers and also because there are a lot of surfers who readily pick up hitchhikers, too. Expect to divide your itinerary into a number of shorter rides, because drivers aren't usually going very far.
West towards Sagres, Villa Do Bispo
Hitching from the center of Lagos will be hard. I have tried it many times, and it seems that the only good way is to walk on the main avenue all the way passing a dozen crossroads until you get to that big roundabout that goes to the motorway towards Faro and Lisbon. Walking from the center of Lagos along that long road will take approx 30minutes. You can try and hitch on the way, but you'll probably have to walk until there. No sign is required as people who stop always ask you where you are going even if you have a sign.
To Sevilla, Spain
On the highway from Lagos to Spain there are not many cars going and most of them are going just localy so it can take you a lot of time to leave Portugal. On the highway there are 4 gas stations in Portugal(on the third station you can dumpster dive some nice baguetes and snadwitches) and some more in Spain. I expected that it will take me only few hours to get to Sevilla but finaly I spent 2 nights on the way! But I was there in december, maybe in summer it could be better.