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There are several ways to get out of the city centre and onto the main highway. If you stop a car that is not going a long distance, then it is best to aim for the Mahmutbey toll booths in the northwest of Istanbul where the E80 really begins.

Get to the Mahmutbey toll booths (Mahmutbey Gişeleri) where it is possible to stop long-distance cars and trucks.

Strictly speaking, pedestrians are not permitted here; if a bored traffic police officer asks you to leave, but ignore him and feign misunderstanding, and walk a few metres away and thumb.

You can take bus 83O* from Taksim Square to the big bus station ''Bayrampaşa Otogar'' on the European side, which is just along the motorway to Edirne / Bulgaria. Take the bus to the last stop, get off and walk back to the entrance. Or even better get off one stop before the last: you will recognize it when the bus is passing from small urban street to a big 3 lanes road. From there, you'll be hitching directly along the motorway. A sign works well here, and there is plenty of space for drivers to pull over since a lot of buses and minibuses stop for passengers just outside. At the same time you are often disturbed by buses stopping, leaving or parking. While exiting, you'll notice a petrol station to your right that is a possible alternative starting point where you can ask drivers for lifts (or just use the toilet).

==== Third option ====

Get into the metro at Taksim Square and take a train towards ''Haciosman''. This is currently the last station for the trains departing from Taksim. One ticket costs 2,00 TL (~0,80 Euro), or 1.75 TL with an prepay "akbil". But beware of the fact that everytime you change metro's, you'd have to pay the 2TL again! At the ''Sanayi Mahallesi'' station (not to be confused with Atatürk Oto Sanayi which is the last station en route), get out of the Metro. You will find yourself along the ''Büyükdere Caddesi'' avenue. Walk along the main street direction north (watch out for big signs that are leading drivers to the motorway to Edirne. After 3-4 min and passing a military camp you'll see the [[on-ramp]]. Unfortunately, there is no way to cross the street from right to left then by attempting suicide, because the main street is mostly full of fast traffic. If you are not brave enough to do so, walk another 10 min further and cross the street over a bridge and walk back the way along the other side.